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This indicated impairment of division and transcription that explains the extended time of development and finally arrest in development.
The size of EGF-containing endosomes also indicated impairment in maturation, as these endosomes were enlarged in control cells but not in dynasore-treated cells (Fig. 4A).
Moreover, 24 h recording of blood pressure and heart rate indicated impairment in circadian rhythms for animals that were exposed in utero to LP diet and forced to catch-up growth during lactation.
Another study also indicated impairment in PQoL among parents with chronically ill children, particularly among parents of children with heart disease [ 11].
Functional and gene expression studies have previously indicated impairment in oxidative phosphorylation and mitochondrial function in subjects with type 2 diabetes compared to controls [ 29, 41, 42].
Tests of renal function indicated impairment, as shown by elevated serum creatinine (362 μmol/L vs. 44-106 μmol/L) and BUN (29.9 mmol/L vs. 2.3-7.8 mmol/L).
Similar(51)
Baseline DLQI (>10 points) and SF-36 MCS and domain scores indicated impairments in HRQOL.
The most consistent findings of recent investigations indicate impairment of cell-mediated immune function with age.
NH4+ was highly accumulated in these tissues in gs1 2 mutants after NH4+ supply (Fig. 4e), indicating impairment of NH4+ assimilation.
However, detection of THC-COOH only (no THC) does not indicate impairment (NORML [2014b]; Sewell et al. [2009]).
Lexical decision was also intact, indicating impairment in semantic knowledge of vocabulary rather than absence of lexical representations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com