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Thiazolidinedione derivatives (TZDs), such as pioglitazone, troglitazone and rosiglitazone, are indicated for therapy of type 2 diabetes mellitus (T2DM).
Pioglitazone, a Peroxisome proliferator-activated receptor-γ (PPARγ) ligand indicated for therapy of type T2DM, induces vascular effects that seem to occur independently of glucose lowering.
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Conversely, estrogen therapy is no longer indicated for osteoporosis therapy or the prevention of osteoporosis.
According to current guidelines, triple therapy is recommended for all patients indicated for anticoagulant therapy and concurrently receiving intracoronary stent, with different recommended lengths of this triple-therapy period (according to ACS presented and type of stent used), followed by a period of combined therapy of OAC and a single antiplatelet drug [ 13].
There were 16,922 individuals who were not clinically indicated for aspirin therapy for primary CVD prevention.
Currently, aripiprazole, olanzapine, and quetiapine are the only atypical antipsychotics indicated for adjunctive therapy in depression.
In exceptional cases, corticosteroids, or a combination of a uricosuricum and allopurinol, may be indicated for maintenance therapy.
Rapamycin is also indicated for the therapy of almost all age-related diseases from atherosclerosis to macular degeneration [ 41, 42].
In patients who were not indicated for thrombolytic therapy, early initiation of treatment to reduce secondary neuronal damage is required for a favorable outcome.
The majority of the participants were female, 26% were obese (BMI ≥30 kg/m) and thus indicated for dietary therapy.
However, in many cases it is best indicated for CAS therapy because a huge percentage of experienced interventionalists use it, and its special features and mechanical advantages, as compared with laser-cut stents, lend to its widespread use.
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