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Some studies [ 3, 16, 17] have indicated adaptation to night shifts on the fourth day, as demonstrated by improvements in cognitive performance at night.
The studies on molecular evolution of leptin indicated adaptation of rodent leptin and insufficient adaptation of human leptin to a diet including large amounts of seeds from grass.
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Subsequently, five researchers experienced in validation tools and screen time evaluated the questionnaire and indicated adaptations and other potentially relevant items.
Matched high glucose metabolism with increased vascularity (coupling) represents a different biological status as compared with mismatched high metabolism and low vascularity, the latter possibly indicating adaptation to hypoxia [31, 32].
By definition, it indicates adaptation of some neural stage(s), but the current data does not allow a precise localization.
For instance, significant divergence in the active site of a protein could indicate adaptation to a new enzymatic function, but it could also indicate loss of function.
Significant increases in iron transport mechanisms and genes involved in various aspects of metabolism indicate adaptation to growth in these conditions.
Of great biological significance, we further noted that activation of Hsf-1 and increased expression of molecular chaperones is accompanied by an increase in cell viability, which is likely to indicate adaptation to the noxious effects of MGO (Figure 5H).
A recent theoretical model by van Doorn and colleagues suggests that speciation in the face of gene flow may be facilitated by females preferring males on the basis of traits that indicate adaptation to the local environment [25].
However, some of the variability derives from genetic factors, indicating adaptation to longer-term stresses.
Many of these are host species specific, indicating adaptation to the specific host response to infection.
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