Expression of endothelial and mesenchymal markers (ANGPT2, CHI3L1) indicated a stronger contribution of the micro-environment to the manifestation of the mesenchymal subtype than the tumor biology itself.
The evolution of the PSDF indicates a strong contribution to the mass of coagulation-mode by the nucleation-mode particles.
Specifically, a high value in a particular voxel indicates a strong contribution to the discrimination boundary but does not necessarily imply greater activation in either condition.
Tnf and Il1b were the genes with the highest positive coefficients in the discriminant vector indicating a strong contribution of these two genes in the multivariate separation model).
The rapid increase in the incidence of EA over the past few decades in Western countries may indicate a strong contribution of environmental factors to the etiology of EA [ 21], but genetic factors may also play a role.
An overexpression of DNMTs has previously been reported in HCC, in precancerous cirrhotic lesions and in dysplasias, indicating a strong contribution of epigenetic events in HCC development [ 6, 7, 11, 33, 63].
Similar to our study, when samples were spread over time (2 weeks to 1 year), ICCs were low (0.02 0.3), indicating a strong contribution of within-person variability (Griffith et al. 2011; Harris et al. 2010; Meeker et al. 2005; Sexton and Ryan 2012; Whyatt et al. 2009).
On RNA level, Tnf was also identified as important marker in the discriminant vector indicating a strong contribution in the multivariate separation model; however, when studying all pairwise gene models, measurements of Ccl7, Il1b, and Il18 were most significant for differentiation between skin rejection and skin inflammation on POD 5 on mRNA level.
This indicates a stronger contribution of sensorimotor representations to assessing the sensory consequences of pain.
