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The ECOG trials combining 5FU bolus injection with streptozocin indicated a response rate of 63 and 45%, with median survival of 17 months in both cases (Moertel et al, 1980, 1992).
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This resulted in 216 unique replies, indicating a response rate of 36%%.
The sample consisted of 477 teachers, out of which 471 fully participated, indicating a response rate of 98.7%%.
Out of these, 16 questionnaires were rejected as they were incomplete, indicating a response rate of 63.6%.
The questionnaires from 32 men were rejected since they were incomplete, leaving 90 complete and evaluable questionnaires, indicating a response rate of 72%.
For the supplementary study with ambulatory measurements of BP and physical activity, for which a much smaller sample size was aimed at, 182 participants were included, indicating a response rate of 66%.
During recruitment there were 173 PWID who were approached but declined to participate; if we take a conservative assumption that all 173 met the inclusion criteria, this would indicate a response rate of 71% (420 ÷ (420 + 173)).
The results indicated that capecitabine achieved a response rate of 30%.
Using CA125 concentrations to indicate response, capecitabine resulted in a response rate of 29% in a population of 28 evaluable patients.
A small number of studies indicate a typical response rate of approximately one third [13, 14], but response rates are difficult to measure, as recruitment to GPS based travel surveys is often conducted within the framework of traditional travel surveys.
Early association studies between mutational status and response to Aza indicate a higher response rate for TET2-mutated patients and a lower response rate for ASXL1-mutated patients.
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