If the chorale tune indicates a modulation (accidentals are sometimes trigger signs), then your cadences must be in the modulated key.
In our study we found laminin gamma 1 (Land1) and TIMP 1 to be significantly down regulated (−1.4 fold and −1.5 fold respectively) by TNFα indicating a modulation of the extracellular matrix.
The gene ontology analysis (Table 2) indicates a modulation of cell signalling pathways has taken place.
Notably, we observed a significant change in size distribution of aggregates indicating a modulation of the abundance of different oligomeric species.
6 Our data clearly indicates a modulation of the 14-3-3ζ 14-3-3ζ 14-3-3ζinterandion by dual acetylation at Lys9 and Lys14 (Fig. 2B).
We observed similar C5aR expression on WT and KO BM arthritic cells, which also indicates a modulation of receptor expression by C5a amounts in the periphery.
However, the observed changes were seen at the motor hotspot of the ECR and not on the periphery of the representation, which would indicate a modulation of the ECR representation itself.
Since leukocyte rolling is predominantly mediated by adhesion molecules of the selectin family, the reduction of leukocyte rolling by APC may indicate a modulation of selectin expression on leukocytes and the endothelium.
Similar results were obtained when co-expression was performed with GFP-SYP121 or with GFP-SYP122 (data not shown) and indicate a modulation of syntaxin trafficking and distribution by the phosphoinositide signalling pathway.
The PCA score plot of all the KOs showed a significant shift after the intervention (MANOVA test, P = 2.00e − 7, Fig. 4a and b), indicating a modulation of the metabolic capacity of the gut microbiota concomitant with its diet-induced structural changes.
