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The modified tester strains, either deficient in nitroreductase (TA 98NR) or overproducing nitroreductase (YG 1021, 1026) or O-acetyl-transferase (YG 1024, 1026), indicated a major contribution of nitroarenes to soil mutagenicity.
A substantial reduction in exenatide clearance was expected given the results of the preclinical studies that indicated a major contribution of the kidneys to the elimination of exenatide.
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For quantum dots smaller than 100 nanometers, the peaks become strongly nonperiodic, indicating a major contribution of quantum confinement.
The δ13CPDB values are largely but slightly negative and restricted near 0‰ (14 out of 17 are between − 3.0‰ and 1‰ mean value − 1.2‰; Table 3) which may indicate a major contribution from a marine carbon source (Keith and Weber 1964) and minor from other sources.
These findings indicate a major contribution of the genetic background of the host to influenza A virus infections.
The slow-recovering populations yielded τ 63×)/τ(100×) = 1.09 and 1.05 for paxillin and vinculin, respectively (Figures 2C and 2D); the fact that these values are significantly below 1.63 indicates a major contribution of exchange to the recovery.
The measured abundances are consistent with natural values and do not indicate a major contribution due to a neutron fluence during reactor experiments.
In conclusion, the low frequency as well as the low level of heteroplasmy of the somatic mtDNA mutations in renal carcinomas does not indicate a major contribution of these alterations in tumour development.
Such effect is similar to that described by Wasserman et al. [ 28] for the incremental effort test and may indicate a major contribution of the anaerobic metabolism for the exercise with the involved limb.
Nevertheless, the votes this spring indicated a major shift.
While there is no doubt that obesity has a genetic component, its rapidly increasing prevalence indicates a major environmental contribution; the etiology and familial patterns of obesity and diabetes are thus of great interest.
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