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Furthermore, sudden strong activity attenuation has always indicated a disruption, even before any alterations in chemical parameters were affected.
The rise in plasma and liver tissue extract concentrations of choline and phosphocholine, together with decreased lipids and lipoproteins, after SWCNTs treatment indicated a disruption of membrane fluidity caused by lipid peroxidation.
However, in exposed animals, a decrease in biliary cholesterol clearly indicated a disruption in cholesterol export through the gall bladder.
Activations in these regions were increased in SAD patients at the beginning of the emotion discrimination task, which indicated a disruption in this emotion regulation network.
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An activity decrease here during overwhelming flashback experiences could indicate a disruption to normal executive processes, or might reflect disrupted patterns of input and output to and from other flashback-affected areas.
Newly published data indicate a disruption in the sarcoplasmic reticulum (SR) following a single bout of SIT [29].
These findings indicate a disruption in inhibitory and switching processing efficiency in the high anxiety group, and are in agreement with top-down processing biases of attention theory.
The proliferation indices for these lesions showed modest increases over normal epithelium, and positive p53 staining was evident in 4 of 10 cases, indicating a disruption of the keratinocyte cell cycle in these lesions.
If the behaviour of the infant does not appear to the observer to be coordinated in a smooth way across episodes to achieve either proximity or some relative proximity with the caregiver, then it is considered 'disorganised' as it indicates a disruption or flooding of the attachment system (e.g. by fear).
The observed defects (especially in complex I) indicate a disruption in this process.
In addition, immunostaining of Hes1 on back skin sections revealed a loss of staining in Rbpj/Tgfb3-Cre hair follicles at P8, indicating a disruption of Notch signaling in the follicular lineages (Figure 3E).
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