Among 1175 participants in the 10 countries reporting frequent migraine – on more than five days per month, indicating unambiguous need for preventative medication – fewer than 20% had seen a health-care professional (general practitioner [GP] or specialist).
The resolution of the branching order is high, with all trees having mostly bifurcations (indicating unambiguous branching) and only a few tri- and multifurcations (indicating uncertainty in branching order).
The resulting set of constitutional assignments indicates how unambiguous NMR would have been able to describe the originally suggested molecule.
The membership probabilities can be used to describe the clarity of differences between the two groups via the summary statistic entropy, which ranges between zero and one, where a value close to one indicates an unambiguous grouping [ 12].
The phylogenetic reconstruction of the oral microbiome did not indicate clear and unambiguous divisions based on a furthest neighbor clustering approach (whereby sequences are included in an OTU only if they meet a similarity threshold for all members of the cluster).
The availability of easy methods of phage isolation from natural sources and the relatively low number of bacteriophages necessary for the generation of unambiguous signals indicate that it is reasonable to use phages in this kind of assay.
However, these studies all used relatively simple protein mixtures or even single proteins, indicating that the unambiguous characterization of peptide glycan structures at the proteome level is still rather challenging.
However, in the latter studies acute and late radiation toxicity was also significantly enhanced in the accelerated treatment arms, indicating that an unambiguous therapeutic benefit for accelerated treatment schedules in head and neck cancer has not been proven (Beck-Bornholdt et al, 1997; Haffty et al, 1997; Horiot et al, 1997).
However, such symptom characteristics are rarely unambiguous, but merely indicate disease probability.
In conclusion, symptom characteristics are hardly ever unambiguous, and mostly the characteristics merely indicate a given probability of disease.
