The overrepresentation of lncRNAs among upregulated transcripts in Spr reflects their substantial contribution to the testicular transcriptome divergence between species, and indicates their functionality in species-specific spermatogenesis regulation.
MicroRNAs are known to play an important role in various physiological and pathological processes, such as apoptosis, cell proliferation, and differentiation, which indicates their functionality in carcinogenesis as tumor suppressor genes or oncogenes [ 8].
Quantitative estimates of the surface area-to-volume ratios of nanoporous layers with different Pt content indicate their relative functionalities for surface area driven applications.
Lastly, as genes can be associated with GO terms reflecting different functionalities which indicates their participation in several functional contexts, we suggest Individual Coverage (IC) as a quantity which measures how well the functionalities of the individual genes are covered.
A protease assay, conducted to confirm their functionality, indicated that both recombinant proteins had proteolytic activity.
OI responses indicate antibody functionality rather than simply their amount, so the similarity of these measurements between all three groups suggests that RA patients receiving ABT still benefit from receiving the PPSV23 vaccination, even though they produce less IgG in response to it.
In addition, the presence of a protein cannot be implied to indicate its functionality as pathogenicity can be caused by functional problems not affecting the stability of the protein [Mangold et al., 2005; Raevaara et al., 2005].
Besides expressing neuronal markers including SV2 and VAChT, as shown above, these cells show clear mature neuronal morphology that may also indicate neuron functionality.
Alternatively, estimates of selective pressures acting on such genes might indicate whether functionality is preserved [ 22- 26].
Does OR expression in a given ectopic tissue indicate specific functionality?
