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As a case in point, if your book is about global warming, the title can be 'Coats are Useless': The uselessness of coats indicate the impossibility of winter since we wear coats in winter.
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After being annealed at 600 and 800 °C, only weak crystalline planes such as hexagonal (101) appear [22, 23], indicating the impossibility of converting the 10 nm La2O3 film into complete crystalline phase.
By early 1980s the data indicating the impossibility of a spontaneous synthesis of long polynucleotides in prebiotic conditions started to accumulate.
Thus, path models which provided a good account of the observed data were indicated by the impossibility of rejecting the null hypothesis (p>0.05); likewise a good fit of the model corresponded to low values (p<0.1) for the root mean square error of approximation (RMSEA).
13 patients (20%) had initial endoscopic treatment of the disease; nonsurgical oncological therapy had been indicated due to the impossibility of complete resection of the tumor or because patients rejected radicalization procedures.
A second point is the impossibility of blinding in data recording.
Now we can see the point of Kripke's analogy between the impossibility of a private language and the impossibility of central planning.
Findings by Shibusawa et al. [ 43] seem to indicate a lack of cytogenetic markers in the rearranged region, which could explain the impossibility of confirming the existence of chromosomal rearrangement on CJA6 by cytogenetic means.
But perhaps the impossibility of the task is the point.
The position of the 2D band at 2729 cm−1 along with the impossibility of its approximation via only one Lorentz line [27] as well as ratio I(G /I 2D) >1 [28] indicate the multilayer nature of electrochemically produced N-graphene.
Call it the impossibility of hope.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com