Sentence examples for indicate the essentiality from inspiring English sources

This experimentation could indicate the essentiality of these motifs for the formation of the transporter pore and the interaction with the substrates.

These results indicate that the essentiality of a given gene or protein does not depend only on its multifunctionality, perhaps there are some other parameters which influence the gene/protein essentiality.

This analysis indicated that the essentiality of B was highly specific to cell lines harbouring gene A deficiency, and hence B is synthetic lethal in the context of deficiencies in DDR genes.

To take this factor into account, we modify (1) as follows: (2) P E = (1 − g ) [ 1 − (1 − ρ ) e − 2 λ t ], where the parameter ρ > 0 indicates the process of rapid essentiality in the early stage after gene duplication.

The majority of these genes (75.1%) are located on the leading strands of the C. resistens chromosome, with 68.8% of all candidate essential genes being located on the left replichore, clearly indicating the prominent role of gene essentiality in bacterial gene-strand bias [ 28].

These results show the essentiality of nutrient sensing for mTORC1 activity in mice and its suppression of PI3K/Akt signaling.

PARP8 knockdown in human cells resulted in cell morphology defects and the most pronounced decrease in cell viability of all PARPs [72], which may indicate its essentiality and explain its wide distribution.

The AUCs of the in vitro models iNJ661m and iNJ661 were not significantly larger than those of random predictions (0.50), indicating the inability of these networks to predict in vivo essentiality.

Only [ 16] demonstrated the use of a quantitative measure of metabolite essentiality known as the "flux-sum" which indicates the turnover rate of a particular metabolite.

The basic premise in these is that, the inability of the bacterium to survive due to the disruption of gene expression by the inserted transposon indicates essentiality of the disrupted gene.

The absence of literature citations for specific modifications indicated the need for possible future experimental work to link metabolism and gene essentiality data.