Exact(2)
Gray dots indicate potent kinase-inhibitor interaction (i.e. active compounds), with darker shades of gray corresponding to stronger kinase-inhibitor interaction.
Pyronaridine is especially interesting as a component of ACT because in vitro studies using recent isolates indicate potent activity against chloroquine-resistant P. vivax and P. falciparum [20].
Similar(58)
The extracted mucilage at the optimal point effectively scavenged DPPH free radical, and more concentrations of this polysaccharide indicated potent antioxidant activity in a dose-dependent manner.
Results indicated potent schistosomicidal effects against both invasive and immature stages of S. mansoni in infected mice, efficacy being both formulation and developmental stage dependent.
Gratifyingly, the in-vivo profile of these compounds, for example, 7, also indicated potent anti-inflammatory activity with impaired effects on glucose, insulin, triglycerides, and body weight.
At a concentration of 100 nM, for instance, we observed a >100-fold reduction of viral mRNA and antigenome copy numbers relative to vehicle-treated samples, indicating potent inhibition of viral replication.
Product levels <0.3 and ≥0.3 indicated potent and non-potent siRNA, respectively.
Recently, studies investigating the effects of lavender oil in the context of psychiatric disorders have indicated potent pharmacological properties.
The growth of SV-LEC and HMVEC-1A cells were inhibited by >35% after 72 h (P < 0.05), indicating potent anti-lymphatic effects of mTOR inhibitors.
At the time point analyzed, ALT levels were similarly increased in DKO and S5KO mutants, indicating potent hepatocyte damage in both groups.
A comparison of the obtained IC50 data (Table 1) indicated potent activity for the EAF and HMF fractions, with IC50 values of 8.53 μg/mL and 10.53 μg/mL, respectively, which was comparable to that of the commercial antioxidant BHT.
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