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Previous reviews of these trials indicate low quality in respect of these and other methodological and reporting criteria [ 4- 12], and a possible trend from comparing review results of quality improvement over time [ 4].
*Study design is either a randomized clinical trial (RCT) or an observational study (OBS) **Quality scores for RCTs range from 1 to 4. Study scores for OBSs range from 1 to 6. Low scores indicate low quality, high scores indicate high quality.
A question to consider in relation to avoidance of the consequences of an ecological trap (Kokko and Sutherland 2001) is the relative importance of inherited preferences and individual experience: if an individual settles in a territory whose environmental cues indicate low quality but then breeds there successfully, will that be enough to keep it there for the next season?
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A green bar indicated high quality of evidence, yellow indicated moderate quality, and red indicated low quality.
Each paper was scored for these criteria on a scale of 0 10, with ≥ 5 indicating high quality and < 5 <span class="lh lhl">indicating low quality.
The Jadad scale was used to assess the quality of the RCTs included, where a score of < 3 <span class="lh lhl">indicated low quality (Jadad et al. 1996).
The NOS scores for the 24 observational studies ranged from two to three on a scale of zero to nine, indicating low quality.
Score: The maximum AMSTAR score a review can receive is 11 (11 for meta-analyses and 10 for systematic reviews) Quality: Scores of 0 to 4 indicated low quality, 5 to 8 moderate quality, and 9 to 11 high quality.
It is widely assumed that low TEER indicates low quality of cultured epithelial cells; however, here we clearly demonstrate that excessive transepithelial resistance in cells originating from a leaky epithelium is associated with a sub-differentiated culture status.
By contrast, the majority of the unmapped reads from the 5 and 1 pg Mondrian libraries (Additional file 1: Figure S2) could not be assigned to the FOCUS database with the exception of some Mycoplasma pneumoniae assignments, indicating low quality reads at the lowest inputs (Additional file 1: Figure S2).
SNPs with Rsq ≤ 0.3, indicating low-quality imputation, were discarded.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com