(Roughness in the animals' lungs might indicate disease).
The pills' effects on my ovarian cancer were to be measured by the CA-125 blood test, in which numbers above 35 indicate disease growth.
Either level of this enzyme – increased or otherwise – can indicate disease or intoxication.
Repeat laboratory tests that would indicate disease progression were not available for all patients, presumably because they were not ordered.
The Bangalore-based start-up, founded by Prahalad Achutharao and Dr. Asoke Taulkder, just closed the $1.7 million seed round to further develop iOmics, an app which researchers can use to analyse DNA and identify diagnostic markers that indicate disease.
However, activity measures may be improved over 5 years while measures of damage, such as radiographic score, indicate disease progression.
The company is developing diagnostic tests for early stage osteoarthritis (OA) and genetic markers that indicate disease severity and future risks, as well as the most appropriate treatments.
In a variety of different conditions such as congestive heart failure, coronary artery disease, and inherited arrhythmias, such changes have been demonstrated to indicate disease progression or an adverse prognosis [8, 29 35].
The team also demonstrated that 1H-NMR can indicate disease severity: They accurately assigned another 76 patients to one of three categories--mild condition (one artery affected), moderate (two arteries in trouble), and major (all three coronary arteries clogged).
The total and ANA sub-serology tests also facilitate differential diagnosis and its refinement [1], predict incipient disease [2], indicate disease severity or impending flares [3], serve as prognostic markers for further organ involvement [4], monitor efficacy of therapy [5], and asses induction of autoimmunity by drugs [6].
Absolute levels of, or changes in, such molecules can indicate disease (the increase in glucose seen in diabetes mellitus), particular conditions (new hormones produced in pregnancy) or increased risk of a disease (screening cholesterol levels can predict risk of coronary heart disease).
