Sentence examples for indicate defective from inspiring English sources

Despite the lack of a hexamerisation defect in crosslinking experiments, this effect could indicate defective intermolecular interactions that can be overcome once the hexamer is formed.

By contrast, mutants displaying accumulation of the Rsp5WW3-HECT∼Ub intermediate would indicate defective ligation.

Alternatively, this fact may indicate defective surveillance; countries that do not detect primary cases may not detect secondary cases.

The lack of ADAMTS13 expression in the plasma from patients with hereditary TTP may indicate defective synthesis, impaired cellular secretion, or enhanced degradation in the circulation.

We anticipate that further study and understanding of the clinical and biologic features of BRCA-mutant PAC will aid in the identification of tissue biomarkers indicating defective tumor DNA repair pathways in sporadic PAC.

In this situation, the appearance of pneumococcal sepsis indicates defective protection against pneumococcal invasion.

Two days after transfection, we scored cells containing two or more distinct nuclei indicating defective mitosis (Figure 6).

The decrease in BrdU uptake in NFAT5−/− cells indicated defective DNA replication, which was in agreement with results by Go et al. showing reduced 3H-Thy incorporation in NFAT5-deficient lymphocytes under osmotic stress [24].

A distance of >1.5 microns indicates defective SCC.

Increased mitotic index in the presence of colcemid indicates defective COC.

These protein aggregates exhibit features indicating defective degradation of misfolded proteins.