Overall, the best compounds 21 24, in particular compound 22, have efficacies and selectivity indices with respect to normal cell lines that indicate considerable potential for use as therapies against apicomplexan parasites.
Pre-clinical and early clinical data for one of these CMTs, COL-3 (formerly CMT-3) indicate considerable potential for this group of anticancer agents.
Furthermore, the applicability of the proposed method in river water and biological samples are successfully verified with good recovery and reproducibility, indicating considerable potential for its practicality in complex real samples.
The results demonstrated that the glycol chitosan derivative was effective at nucleating and stabilising luminescent CdS QDs in aqueous colloidal dispersions under acidic, physiological, and alkaline media, indicating considerable potential for biomedical and pharmaceutical applications in nanomedicine.
Finally, it was demonstrated the feasibility of synthesising fluorescent CdS QDs in aqueous colloidal dispersions at physiological pH, indicating considerable potential to be used as biomarkers for biomedical and pharmaceutical applications in nanomedicine.
The improved definition of the CSF proteome presented here indicates considerable potential to expand the range of useful measurements for diagnosis, assessing treatment responses and understanding underlying disease processes in HIV infection.
The results indicate considerable conservation of resources and a considerable growth potential.
Moreover, our observations indicate the considerable potential of porous organic polymers (POPs) as a new generation of heterogeneous catalytic platforms that may prove effective when targeting important but highly challenging reactions.
Several studies have reported the predictive value of the levels of CRBN-binding proteins regarding the response to IMID therapy and survival outcomes in patients with MM, indicating their considerable potential for use as biomarkers.
Furthermore, the newly-designed electrode presented a fast response time of 10 s with a lifetime of at least 2 months indicating no considerable potential divergence.
