Taken together, our data indicate that a pool of AGS3 is phosphorylated in the GPR domain and that this modification is sensitive to the induction of mTOR-dependent autophagy.
Altogether, these data indicate that a pool of UNC93B1 protein exits the ER and traffics through the Golgi in unstimulated cells.
In our comparison of benign and carcinoma tissue extracts, we detected active MMP-2 and MMP-14 forms only in the cancerous tissue samples, indicating that a pool of the tumor MMPs is free of endogenous inhibitors (TIMPs), and is thus likely to contribute to proteolytic events that precipitate tumor metastasis.
Previous reports have indicated that a pool of AMPK is localized at the plasma membrane as a result of myristoylation of its regulatory AMPKβ subunit.
Cbp80, but not Cbp20, was co-purified with eIF4E-bound transcripts, indicating that a pool of Cbp80 exists independently of Cbp20 [ 140].
In contrast, the XAV939-treated samples lost little DNA-PKcs over the range of run times, indicating that a pool of tankyrase-dependent modified DNA-PKcs exists under normal conditions that is not present with tankyrase PARP inhibition.
TLR4 could be readily detected in the cytoplasm of permeabilized keratocytes, indicating a cytoplasmic pool of the protein, as well as on the plasma membrane of nonpermeabilized cells, further indicating active TLR-4 receptor.
Compared to that of the control cells, this LI indicated an important pool of DDB2-deficient cells which started to re-enter the cell cycle and which corresponded to an essentially G1/S subpopulation.
Results for Echerichia coli show that as more data become available, a larger diversity is estimated, indicating an extensive pool of rarely occurring genes in the population.
31 This may indicate that there is a pool of undiagnosed and untreated hypertension in the Peruvian Amazon, perhaps specific to certain ethnic groups.
