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Then, the edges (that is, connections) correspond to a strongly significant interaction between nodes and red edges indicate a negative interaction between two nodes.
Our previous studies also indicate a negative interaction between D1-like and insulin receptors because a D1-like receptor agonist, fenoldopam, inhibits the proliferative effect of insulin in A10 cells [ 13].
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For the lowest inflow rate, the reduction in soil loss by interaction between rainfall and inflow accounted for 20% of total soil loss, indicating a negative interaction.
Similar expression profiles indicate a positive interaction and dissimilar profiles indicates a negative interaction.
(ORi = OReg/OReORg, ORi > 1 indicated a positive interaction (synergy); ORi < 1 <span class="lh lhl">indicated a negative interaction (antagonism); ORi = 1 indicated that there was no interaction).
The value of S < 1 <span class="lh lhl">indicates a negative interaction which is in agreement with what is indicated by RERI = −2.18 < 0 and AP = −0.76 < 0.
In contrast, the triple mutant (S83F-D87G-S80I) contributed 1% less offspring per generation than the parent strain: this indicates a negative interaction between these mutations, with the third mutation wiping out the fitness advantage of the double mutants.
Only TSA treatment correlated significantly with increased H3K4me3 (p < 0.01, Figure 4B), consistent with previous studies that have indicated a negative interaction between de-acetylation at lysine 9 by HDAC activity and trimethylation at lysine 4 (Lee at al., 2006b).
The peak position was slightly shifted to the Hu < 0 region, which also <span class="lh lhl">indicates a negative mean interaction field (Roberts et al., 2000).
The observed nH values are lower than unity (∼0.5) (see Table 2), indicating a negative cooperative interaction between imipramine and each mecamylamine isomer.
A positive interaction indicated more than expected viable cells, and a negative interaction indicated fewer than expected viable cells.
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