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Therefore, our data indicate a major loss of TPH2A 1234 enzymatic activity by RNA editing and support the recently reported 80% reduction of 5-HT synthesis in PC12 cells expressing the TPH2-R441H mutant [29].
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For the unpublished Cochrane reviews, only a minority (13.2%) were published elsewhere, indicating a major loss of information being publicly available, as well as wasted scarce resources.
By Elizabeth Kolbert Graptolites indicate a major die-off.
Quantitative analyses were also applied: less total protein spots and more down-regulated protein spots were detected in the mutants, indicating there might be a major loss of protein in heritable variant rice plants after seed space flight.
It was a major loss".
This is a major loss.
"It's a loss, a major loss," Woodson said.
We would suffer a major loss.
Several people said his departure was a major loss.
Dr. Bernard's passing is a major loss to our community.
The casino was sold at a major loss in 2011.
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