While this observation indicates a challenge for a precise definition of spike-onset in our context, the two different mathematical notions seem to have the same biological effect.
However, adult studies have shown a more clearly peripheral effect of clonidine versus its systemic effect [ 2, 3, 7, 24] indicating a challenge to us for further investigation of clonidine administered in distal peripheral blocks in children.
This indicates a real challenge for the Congolese National diabetes plan.
Even though all interviewees in all cases were aware of the existing intra and inter-organizational boundaries, and improvement projects were started to overcome these, joint delivery of care and services both within and across organizations was indicated as being a challenge for the future at the time of our data collection.
These findings indicate a great challenge in diabetes prevention, particularly for high-risk individuals.
The results indicated that it was a challenge for the teachers, especially in secondary level, to find appropriate methods for supporting students' inquiry efforts.
Other studies, however, have indicated that angina is a challenge for women post MI [ 18, 28].
The finding that overactivity and aggressiveness in patients most strongly predicts the use of seclusion and restraint indicates that this behaviour is a challenge for staff and often the reason for using coercive interventions.
In addition to these five, we observed the reduced expression of the glycolytic enzyme LDHA, which may also indicate another challenge for energy metabolism in these neurons.
These parameters indicate that the environment is harsh and the RSSI measurements is quite noisy, posing a challenge for tracking.
