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To classify the aggregation patterns, we defined two indexes: CELL DISTRIBUTION RATIO (ratio of cells in the central region to those in the peripheral region) and PERIMETER RATIO.
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These include the higher mitotic index, cell proliferation (Ki-67) index, and existing neoplastic dura cells around the craniotomy site (Wiemels and Wrensch 2010; Bir et al. 2016; Simpson 1957).
These IC50 values for arsenate were then 32 µM, 19 µM and 19 µM for Shape Index, Cell Area and EGFP expression respectively (no significant Roundness effect).
Laboratory examinations included hemoglobin, red cell indices (Cell Dyne 3000, Abbot) and manual reticulocyte counts.
The proliferation index, cell numbers of B16 cell line, was elevated obviously by α-MSH treatment [ 25].
The CCS method was able to index cell cycle phase distribution even for an independent cell cycle dataset derived from a different cell line and a different platform.
We developed a signature-based method for indexing cell cycle phase distribution from microarray profiles under consideration of cycling and non-cycling cells.
Antibodies were added in three-fold titration starting from 5 µg/ml, and the cell index (cell growth) was monitored continuously for 2 days.
The Cytotoxicity Index is the maximal of nuclear morphology index, membrane permeability index, lysosomal mass index and cell density index, for each well.
For heterogeneous refractive index cells, it is possible to use a coarse approximation on the cell refractive index [ 4].
For analysis of the binucleation index, cells were fixated after overnight adhesion to the dish.
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