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The Lac (1.3 ppm) is an end product of anaerobic glycolysis; thus the increase in Lac concentrations often serves as an index of altered oxidative metabolism, that is, in ischemia, hypoxia, and cancer [ 6].
Hence, downregulation of Pcdh10 gene expression observed in this study is an index of altered cell-to-cell communication, which may also signify disturbances in synaptic or neuronal plasticity within the striatal complex.
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Since the suitability of the indices for detection of altered β-cell function may depend on the SNPs' pathomechanisms, we additionally analysed the SNPs affecting GSIS separately from those affecting the incretin axis (ISIS or incretin release).
P14 TCR-transgenic mice have been extensively used for analysing T cell responses to the index peptide, gp33, and a range of altered peptide ligands (APL), including antagonists and strong, weak and partial agonists previously shown to elicit a wide range of biological effects [ 9].
A bolt of altered perspective.
Thus, any degree of comorbidity index simplification substantially altered the magnitude of the association observed between comorbidity and the outcome.
Therefore, the primary aim of this study was to determine the effect of altering the glycemic index of a meal on postprandial glucose control in children with type 1 diabetes receiving multiple daily injection therapy.
The group that decides on the index's components have done a good job of altering the gauge to reflect the modern economy, he feels, even as they get a bad rap from critics who deride the index as stodgy.
A chained CPI inflation index would alter the way cost-of-living adjustments are made for Social Security recipients, slowing increases and reducing the benefits for seniors and the disabled.
Moving to a "chained CPI" inflation index would alter the way cost-of-living adjustments are made for Social Security recipients, slowing increases and thereby reducing the benefits for senior citizens and the disabled.
Collapsing categories of a comorbidity index can alter inferences concerning comorbidity as an exposure, confounder and effect modifier.
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