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Apex masses were submitted to the BinBase algorithm using the settings: validity of chromatogram (<10 peaks with intensity >107 counts per s), unbiased retention index marker detection (MS similarity >800, validity of intensity range for high-m/z marker ions), retention index calculation by 5th-order polynomial regression.
Serum MMP-9 levels are gradually increasing with progressing coronary ischemic symptoms [24] and might be useful as an index marker of plaque activity in patients with known CAD [25].
In every sample, 3 µL of the retention time index marker (n-alkanes ranging from C10 to C36, each 200 µg /ml in pyridine) was spiked to determine the retention time index (RI) [18].
The cell proliferative index marker Ki67 was estimated at 15%.
Thus, skin AF values may be used as an index marker of long-term glycemic control compared with HbA1c.
Several SNPs (e.g. in APOE, CETP, LPL, APOB and LDLR) influenced multiple phenotypes, while others (e.g. in F7, CRP and FBB) showed restricted association to the index marker.
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The innovative feature helped divers to calculate the time of immersion, thanks to a graduated scale with embossed numerical index markers positioned at each of the four cardinal points.
For his temporal hour system watch, Mr. Kikuno created the first hand-winding wadokei with a mechanism programmed over a year that can lengthen and shorten the space between moving index markers.
In 2011, Mr. Kikuno presented three of his watches at the A.H.C.I. booth at Baselworld: a highly complex perpetual calendar tourbillon and two innovative watches inspired by the traditional temporal hour system used during the Edo period (1603-1868) in Japan, with a mechanism programmed over a year that increases the space between moving index markers.
There are other minor differences between the Activité Steel in the Activité, such as the index markers and the hands.
Differences were observed between the T2DM and control adolescents in the way DI changed over time (p =.02).β-cell function in adolescents with recently diagnosed T2DM was impaired with no improvement of β-cell function over the 2 years of study despite stable Hemoglobin A1c, body mass index markers of insulin sensitivity, and standard treatment of hyperglycemia.
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