Embryos exposed to the high concentration of PBO had an elevated deformity index (effect of PBO alone on deformities, tied p = 0.0448).
Embryos exposed to FL alone did not exhibit elevated deformity indices (tied p = 0.3764); BNF at this concentration also did not cause an elevated deformity index (effect of BNF alone on deformities, tied p = 0.1681).
Coincident with this decline, embryos exposed to 50 and 100 μg/L BNF exhibited elevated deformity indices (effect of BNF on deformities, tied p < 0.0001).
Embryos exposed to 10 μg/L ANF and 100 μg/L ANF exhibited no deformities, whereas those exposed to ≥500 μg/L ANF exhibited high deformity indices (effect of ANF on deformities, tied p < 0.0001).
Since most cytotoxic drugs have a low therapeutic index, additive effects of multiple low fold changes in drug resistance may be sufficient to cause clinical treatment failure.
In the present study, we used FDG-PET rather than a more specific marker of microglial activation such as PK11195 to index the effects of inflammation on resting brain function.
We attempt to explain the observed trends (i - v) based on the geometry, scatterer si - vnd relative refractive indices; additional effects of the different refractive index profiles (random particulate versus random continua) may also contribased
Models for FIL, HOMA-IR, and Matsuda index demonstrated independent effects of the index, gender, BMI, and the interaction between index and race in predicting GDR.
For Matsuda index, SIisOGTT, and Strumvoll indices, the independent effects of the index, gender, and BMI could explain a greater degree of variability in GDR, ranging between 33.3% and 36.5%.
The model for Stumvoll index indicated independent effects of only the index and gender.
