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The structure of the load balancing system is composed of three design agents: the load index agent (LIA), the resource management agent (RMA) and the load transfer agent (LTA).
Associations between index agent and medication possession (logistic regression) and days covered (linear regression) were evaluated.
"Index agent" was defined as the first agent filled; "index date" was defined as the fill date.
Failure to refill the index agent within the initial 90 days was a strong predictor of poor persistence.
The number of infusions was tabulated from follow-up period medical claims with evidence of index agent administration.
This was done by summing the imputed days supply for all index agent fills that occurred between the index date through day 358.
Similar(51)
Of 42 427 patients who had a prescription fill for one of the index agents during 2004, 7873 were eligible and were retained for analysis (Table 1).
The MarketScan Medicaid Multistate Database was used to identify adult RA patients who used etanercept, adalimumab, or infliximab (index agents) from 2007 to 2011.
A more comprehensive study manipulating all five indices (agent, time, place, causality, and intentionality [goal-relevance]) may give a clearer picture of the effect of each of these event indices on attention.
Still, if a patient query tool could be developed that was largely accurate for revealing refill history early in therapy, it might serve well as a screening tool to identify patients who are unlikely to achieve appropriate therapeutic coverage on their index prostaglandin agent and require encouragement towards persistence or a physician-directed change in therapy.
In the current study, we only manipulated two of the five indices of the event indexing model (agent and causality).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com