Sentence examples for indeterminate significance from inspiring English sources

Another potential role for USE is for nodules with non-diagnostic or indeterminate cytological results on FNAC (e.g., cellular atypia of indeterminate significance), which affects approximately 30% of FNACs [61, 62, 63].

Altogether we scored the variant as of Indeterminate significance [ 4].

A CT scan of the chest demonstrated punctate lung nodules of indeterminate significance.

Lung nodules of indeterminate significance are discovered in over 25% of the individuals screened with CT.

Experts spoke of overdiagnosis as being of indeterminate significance because of uncertainty about the overdiagnosis rate.

Thirty-five percent (51/145) of subjects had at least one lung nodule of indeterminate significance with subsequent CT control.

The association of tumor size with malignancy in thyroid nodules with indeterminate cytology (atypia of undetermined significance [AUS]/follicular lesion of undetermined significance [FLUS], suspicious for follicular neoplasm [SFN]/Hürthle cell neoplasm [HCN], and suspicious for malignancy [SM]) has not been clearly studied.

Overall, these data suggest that NPM1 mutations are a secondary or late event in the pathogenesis of AML and are preceded by founder mutations in genes that may be associated with recently described preclinical states such as clonal hematopoiesis of indeterminate potential or clonal cytopenias of undetermined significance.

Repeat FNA is the usual management for aspirates in the category of "atypia of undetermined significance/follicular lesion of undetermined significance" (TIR3A according to the update version of the SIAPEC-IAP (Nardi et al. 2014)) due to a 5%15%% risk of malignancy, with diagnostic lobectomy considered for nodules with repeatedly indeterminate FNA cytology (Nishino 2016).

Low-dose helical CT scanning identifies early stage lung malignancies and also a large proportion of lung nodules of uncertain diagnostic and prognostic significance (ie, indeterminate nodules).

Cerebral artery aneurysms have also been reported and cerebral magnetic resonance imaging (MRI) has shown an increase in lacunar infarcts at a younger age as well as focal hyperintensities of indeterminate aetiology, although the clinical significance of this is uncertain [ 19].