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Indeterminate lesions.
Indeterminate lesions with high suspicion of malignancy were considered as malignant.
FDG PET-CT is effective at detecting occult metastases and characterising indeterminate lesions.
FDG PET-CT characterisation of indeterminate lesions on CT/MRI as benign, allowing curative resection to be attempted.
By detecting occult metastatic disease and characterising indeterminate lesions, FDG PET-CT can have a major influence on clinical decision-making in primary and recurrent biliary malignancy.
Due to a significant overlap with other commoner and similar appearing hepatic lesions, hepatic tuberculosis is often either misdiagnosed or labelled as indeterminate lesions.
It detected occult sites of disease in 24 patients, helped to characterise 7 indeterminate lesions on cross-sectional imaging and detected 2 incidental synchronous primary cancers.
Despite these issues, we found FDG PET-CT to be reliable in characterising indeterminate lesions and discriminating between benign and malignant disease with few false-positive results.
In a further seven patients, FDG PET-CT clarified indeterminate lesions seen on cross-sectional imaging as either malignant (n = 2) or benign (n = 5).
Magnetic Resonance Imaging (MRI) is an essential problem solving tool to determine the site of origin of a pelvic mass and then to characterize an adnexal mass, especially in patients with indeterminate lesions [13, 14].
All patients in whom SPECT/CT had been performed had indeterminate lesions in the lumbar region on planar scans which in most cases corresponded to degenerative disease of the spine as to be expected in the age group studied.
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