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Likewise, 10 min exposure to Benzonase was sufficient to disperse aggregates independently of sequence.
Our method aims to combine the advantages of Cavbase with the smooth nature of a Gaussian pharmacophore representation, thus enabling binding site comparisons independently of sequence homology.
We showed that this observation is independently of sequence length as long as miRNA target predictions are filtered by the hetero duplex folding energy.
Interestingly, the occurrence of the novel motif in a transcript's 3'UTR significantly increases the number of predicted miRNA targets independently of sequence length.
This is done independently of sequence order.
Sequence-specific DNA-binding proteins such as ORC are thought to play an important role in establishing the local chromatin architecture by influencing the positioning (and possibly modifications) of histones, which bind DNA independently of sequence.
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Further, we find that potential off-target-sequences occur independently of protein sequence conservation.
In principle, one could also use exact calculation by determining all possible nucleotide sequences that encode a given amino acid sequence, calculating the probability of each nucleotide sequence under the assumption that codons are used independently of the sequence context, and then summing up the number of repeats in all nucleotide sequences after weighing for the probability of each sequence.
Studies of gene duplicates in yeast first showed that regulatory sequences evolve independently of coding sequences in duplicated genes [ 61] and suggested that changes in expression level are the first step in gene retention [ 62].
Within certain constraints, the base sequence for the binding site of the control oligonucleotide (labelled OBS in the Figure 2) can be chosen independently of the sequence on which the nucleic acid enzyme will act.
In the present case, e.g., answers need to be rated correct independently of the sequence the accounts are listed in the T-account.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com