Sentence examples for independently of dose from inspiring English sources

Efficacy was evaluated at the beginning of each plitidepsin cycle, independently of dose delays, up to 6 cycles of treatment.

Furthermore, Western blot analysis showed that Bcl-2 levels in the mitochondria-enriched fraction remained on an equally high level independently of dose in 70Z/3Bcl-2+ 70Z/3Bcl-2+

Surprisingly, these histological lesions were observed in all contaminated groups including the lowest exposure of 0.96 mg/L, independently of dose.

In macroscopic examination, we observed that the organs of mice exposed to (PhTe 2 (independently of dose and period) had a gray-black coloration.

Pigments increased with fertilization independently of the dose supplied but only significantly with soil nitrate as covariate.

Clonal composition was altered by mechanisms that blocked the local propagation of clonotypes independently of antigen dose and not as a consequence of interclonal competition.

In this study, transient grade 3 elevation of conjugated bilirubin, without concomitant elevation of other hepatic enzymes, was reported in 3 (4 %) of 69 patients, and it was described that the elevation of bilirubin appeared independently of the dose level and occurred on day 3 after the first application and resolved spontaneously by day 5 [7].

Finally, fluorescence was measured after 30 min of incubation at 37°C using a microplate Fluoroscan Ascent spectrofluorometer (excitation at 540 nm and emission at 590 nm), as preliminary experiments have shown that maximal fluorescence was obtained at that time independently of the dose of squalamine.

"Nrf2-mediated oxidative stress" seems to be affected independently of TTP dose and time point but ranked first after 24 h.

In patients receiving 180 mg of oral morphine equivalents or more, 39 episodes (73.5%) were treated with doses of 600  μg of OTFC or more in the first instance, producing acceptable adverse effects, which occurred equally, independently of the dose.

The percentage of binucleated cells ranged between 45%56%and64%72%–72% in Vero-E6 and HepG2 cultures, respectively, and no differences were observed between MCLR-treated and untreated cells, independently of the dose.