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Although both nanotopography and co-culture independently enhanced the osteogenesis of hMSCs, osteogenesis was further enhanced by the two factors in combination, indicating the importance of synergistic cues in stem cell engineering.
However, fusion of independently enhanced results will be another open issue.
The addition of dichotomous variables for Killip class (C = 0.78), heart rate (C = 0.73), and systolic blood pressure (C = 0.74) – each as defined for the TIMI STEMI risk score – independently enhanced model discrimination for in-hospital mortality.
Exogenous recombinant active human TGF-β1 independently enhanced tenocyte-mediated collagen matrix contraction in a time-dependent manner.
The results of this study confirmed the hypothesis, showing that TGF-β1 and C-ABC independently enhanced collagen content and tensile properties of engineered constructs.
A 26-article meta-analysis concluded that each 5 μ m homocysteine increase independently enhanced CHD risk by approximately 20%9090).
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Here we demonstrate that the prM/E mutations increase the specific infectivity of chimeric virions and the NS2A/NS3 mutations independently enhance packaging.
Using a 96-well differentiation platform for generating human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) we found that S1P and LPA can independently enhance cardiomyocyte generation when administered at an early stage of differentiation.
The obtained results indicate that the proposed HIS system can be able to independently enhance the mode stiffness/damping, in which the additional bounce/pitch and roll/warp mode stiffness are determined by the difference and summation of the top and the corresponding bottom piston surface area, respectively.
In addition, HIV env can independently enhance HIV replication [2], potentially through NFAT activation [3].
The larger particles (i.e. PM2.5) may result in inflammatory reactions in the small and upper airways alike, and both types of pollution may independently enhance systemic inflammation [38].
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