A liver-specific glucokinase knockout mouse has been constructed as a model for the liver-specific role of glucokinase in MODY2, independent of its function in regulating insulin secretion in pancreatic β-cells.
Together, these data support a model in which the function of APL-1 in molting is independent of its function in neurotransmission.
The role of Hfq in LF82 virulence was independent of its function in regulating RpoS and RpoE activity.
The absence of bent-cotyledons in fas1 seedlings suggests that ASF1 function in the HIRA pathway is independent from its function in the CAF1 complex activity.
The authors show that the function of HOPS in this final stage of fusion is independent of its function in the docking process, implying that HOPS needs to interact only with the SNARE complex for this fusion step.
As shown in Fig. 5C, none of the DDR defective mutants of FancJ affected its interaction with PLK1, suggesting that the function of FancJ in regulating the centrosome cycle may be independent of its function in DDR.
Our results indicate that Ppd-H1 in barley has evolved novel functions in the control of flowering time, which are independent of its function in the circadian clock.
Our results support a role for Aub, independent of its function in RNA silencing, as a component of a nos mRNA localization complex.
A recent study has uncovered that, in several loci of Arabidopsis, Pol IVb's role as the effector of RNA silencing is independent of its function in siRNA biogenesis, and the study proposed that some epigenetic marks of chromatin adjacent to the Pol IVb-targeted region could influence the ability of Pol IVb-guided DNA methylation [62].
We show that MAVS causes apoptosis independent of its function in initiating IFN-I production.
Independent of its function in regulating the HIFα pathway, pVHL also binds other cellular proteins [14], [15], [16] and promotes extracellular matrix assembly [16], [17].
