A potential-independent dissolution current flowed depending on the rotation speed, species and concentration of chloride salts.
The spray-dried granules obtained were reported to have a pH-independent dissolution profile.
The models resulted in plausible successes in fitting/simulating and describing different PK profiles of poorly soluble fluticasone propionate (FP) formulated in various inhaler products, while yielding its lung region-independent, dissolution-controlled slow absorption rate with a half-life of ~3.5 h (Tayab & Hochhaus 2005; Sakagami 2014; Weber & Hochhaus 2015).
Such a relationship is most often found with those modified-release dosage systems that demonstrate an in vitro release rate that is independent of the dissolution media and stirring speeds employed in a dissolution apparatus.
The nanocrystals were optimized using 32 full factorial design considering stabilizer concentration and stirring speed as independent variable and dissolution efficiency as dependent variable.
The results showed that SMEDDS formulation improved the oral bioavailability with reduced pharmacokinetic variability which was mainly attributed to improved pH-independent solubility and dissolution rate.
The optimized formulation showed a pH-independent increase in dissolution rate in SGF and phosphate buffer when compared with a marketed tablet formulation.
I have little doubt that if Bed Bath & Beyond had been around in the eighties providing waterproof MP3 players for the shower, the Soviet Union's dissolution into independent states and the fall of the Berlin Wall would never have happened.
Once the preeminent republic of the Union of Soviet Socialist Republics (U.S.S.R.; commonly known as the Soviet Union, Russiaa became an independent country after the dissolution of the Soviet Union in December 1991.
Once the preeminent republic of the Union of Soviet Socialist Republics (U.S.S.R.; commonly known as the Soviet Union), became an independent country after the dissolution of the Soviet Union in December 1991.
Moreover, a unique reaction scheme has been designed to establish the independent heat effect of dissolution and reaction quantitatively.
