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Treatment therefore is most successful when it consists of two phases: detoxification from the painkillers, followed by a longer (and sometimes indefinite) maintenance phase.
The only intervention that has been repeatedly proven to cut the mortality from opioid addiction by 50% or more is indefinite maintenance with another opioid, typically buprenorphine or methadone.
While some people with opioid addictions do recover through abstinence, indefinite maintenance on drugs like methadone is the only approach that has been proven to reduce the risk of overdose death by 75percentt.
Studies show that making indefinite maintenance treatment with methadone available reduces mortality by over 70percentt among people with heroin addiction; similar results are likely with other maintenance treatments, like Suboxone.
Shortly after the introduction of the SGAs the hope was expressed that these agents, with their reduced propensity for motor side-effects, would carry a small enough risk to warrant indefinite maintenance treatment [ 15].
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Indefinite and stable maintenance of unique conformations—"strains"—in vivo that link structure to patterns of pathology was recently demonstrated, further corroborating prion-like properties of misfolded Tau [ 5, 53].
It said that the building of new houses remained on indefinite hold, but also promised better maintenance of the vacant lots, and included a gift certificate to Publix, the supermarket chain.
Despite the popularity and concept simplicity of TOPSIS, this technique is often criticized on its capability to manage uncertainty and imprecision when using crisp value measurements (Dagdeviren et al. 2009).This issue has led to the implementation of fuzzy TOPSIS to solve maintenance decision-making problems in indefinite or fuzzy environments.
It is now asking the PUC to approve an indefinite, 5% increase in the cities' annual maintenance fees.
Maintenance is the notion of indefinite transmission of virus through members of a host population.
Maintenance encompasses the notion of indefinite transmission of infection within a local population and depends on an average transmission ratio >1.
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