Indeed this variation explains well the cellular heterogeneity experimentally observed in stem cells.
Indeed, this model explains the observation that overexpression of Tpx1 increases the activation of Pap1 by H2O2 (Bozonet et al., 2005).
Indeed, this could explain the absence of significant difference in the NPR between the three cohorts, but would not explain the fact that radiological measurable response was seen in some patients, and not exclusively at the MTD level.
Indeed, this may explain why South Korea has pushed ahead more quickly than Japan.
Indeed, this may explain why the Moscow authorities are allowing it to take place.The ideologists of the protest movement know that its current phase, which began in early December under the banner of "honest elections", is reaching its limits.
Indeed, this might explain why some mothers do not even breastfeed their infants, in the quest to return to work.
Indeed, this might explain why 10 fold reduction of HsOrc2 allows viability [33].
Indeed, this may explain the remarkable lack of overlap in gene expression profiles obtained in several published studies of cells stimulated with wnt3A [15], [16], [16].
Indeed, this might explain the EGFP expression observed in glial cells of both the CNS and PNS in our studies (Figs. 3 and S1)—while the transcriptional vocabulary may be preserved between human and zebrafish, the tissue-specific requirements and corresponding expression patterns may differ.
Indeed, this could explain why, at diagnosis, most tumors have already acquired a certain resistance to apoptosis [ 28].
