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Indeed, substituting alanine for the invariant phenyalanine in the PAM2 motif abolished binding to Hs or DmPABPC1 for all three human TNRC6 proteins.
Indeed substituting F164 to Ala eliminates this interaction, and mixing IsdBN1(F164A -L-N2 F164A -L-N2 F164A -L-N2 slowithrate of hemetHbansferesultsmetHB to indB.
Central to the interface are symmetric hydrogen bonds between Arg474 and Glu478 across the dimer (2.9 Å donor to acceptor; Figure 2B) and, indeed, substituting these residues decreases Rev function (Elinav et al., 2012).
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These results suggest that minor surgery indeed substituted for referrals.
In the enkephalins, for example, Glys can indeed substitute for the d-residue present in the frog opioid peptides.
To investigate whether the AsPBF that we cloned can indeed substitute for ZmPBF's function in OMA 7.06, a transient expression assay in tobacco leaves was performed using plasmids shown in figure 5. To monitor the activation of 27-kDa γ-zein promoter by oat PBF, AsPbf1 was selected as it has higher expression compared with AsPbf2 based on our previous gene expression analysis.
And it clips the wings of technocrats and ideologues who would reduce all political or social questions to economic ones, or indeed substitute economics for politics as such.
Indeed, substitutes may end up being even more frequent with Pocket Shop if your local store is small and frequently runs out of your preferred brand/item.
What is different now is that a growing minority of people in our nation lack all of those things and indeed, have substituted an inflated sense of expectations for a commitment to hard graft".
Indeed, we substitute (hat{mathcal{B}}_{q 1/k_{2}}(F T,m,epsilon))) with (mathcal{L}_{q 1/kappa}(hmapstopsi_{k_{1}}^{mathfrak {d}_{p}}(h,m,epsilon))(tau)), constructed in Lemma 5, for every (0le plevarsigma-1).
Currently, we do not know whether the polyubiquitinated Lys indeed can substitute for the function of the monoubiquitinated Cys-form.
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