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The question of whether CGRP directly activates meningeal afferents or not has been largely refuted; CGRP does not cause firing nor rapid sensitization of meningeal afferents when it is locally administered onto the rodent dura mater, although application of cAMP analogs can indeed sensitize meningeal afferents [32, 33].
Taken together, our data demonstrate that inhibition of BRCA1 expression can indeed sensitize a range of mammalian cell types to proteasome inhibitors in vitro.
According to the protective role of NF-κB, it has been shown that NF-κB inhibition can indeed sensitize hepatocytes to TNF-induced apoptosis by means of JNK sustained activation [ 211].
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From this we conclude that OS cells are indeed sensitized to irradiation whereas normal cells are not.
The results showed that the guinea pigs in the CTCM-treated groups were indeed sensitized and that bronchoconstriction was abolished by CTCM.
We found that ganciclovir indeed sensitized C6-TK and LN18-TK cells to the lethal action of soluble sFAS-L, and this effect was abolished by dexamethasone.
Indeed, hypoxia sensitizes cancer cell lines to DNA damaging agents such as mitomycin C and the poly(ADP-ribose) polymerase inhibitor.
Autocrine TRAIL was indeed capable to sensitize leukemia cells to the pro-apoptotic effects of hypoxia, but not to trigger apoptosis in normoxia.
NTG is able indeed to activate and sensitize spinal trigeminal neurons [18, 20, 21, 34].
Indeed, PERK inhibition did sensitize cells to death by bortezomib.
Indeed, we also sensitized established tumor cells when senescence was induced by chemotherapy within a population of same cancer cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com