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Thus, while caspase 9 is slightly induced following infection with the A. actinomycetemcomitans CDT-mutant strain perhaps in response to the partial DNA damage also observed the damage is compensated for and indeed repaired and does not result in caspase 3 activation as is observed with wild-type infection.
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Under pressure to show his austerity program was indeed repairing the British economy by reducing the budget deficit without choking off growth, Mr. Osborne in March gave the Bank of England more flexibility in supporting the economy without the need to lower inflation in the short term.
Indeed, repairing 6-4PP lesions alone suppressed apoptosis as much as repairing both types of DNA lesions.
Indeed, repairing the mutations in just the three DNA repair genes completely removed the radiation resistance.
Indeed, repair of reduced and oxidized abasic sites proceeds via a "long-patch" FEN1-dependent pathway [16].
These observations strongly support the conclusion that AlkB indeed repairs the m4C adduct to unmodified cytosine.
Evidence to date suggests that these roles are mainly related to STAG1-cohesin [reviewed in (4)] and indeed, repair of inactivating STAG2 mutation to generate normal expression in glioblastoma cells was recently reported to have no significant effect on the transcriptional profile, suggesting that the role of STAG2 may be restricted to its functions in chromatid cohesion (1).
"They keep on breaking and it's not like I can nip down the local shop to get them repaired …" Indeed.
And indeed, the Union Army soon repaired the damage from the raid and reinforced its grip on Confederate Missouri.
Geron plans to inject its oligodendrocytes into the damaged spines of patients between one and two weeks after their injury.Tests in rats, using human cells, have shown that oligodendrocytes injected this way can indeed help repair myelin sheaths and restore the ability of nerve cells to carry signals.
In later research, AlkB was indeed shown to repair these adducts in RNA both in vitro and inside cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com