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Indeed, most frequently, TP53 mutations were shown to be associated with prognosis in Asian populations infected by HBV, 44 46 whereas in a series of patients with mixed aetiologies, TP53 mutations were usually not an independent prognostic marker.
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The researchers explain that, to do this, they "focused on three common discourse markers … (I mean, you know, and like) and two filled pauses (uh and um)." They recorded and transcribed interviews with the speakers, noted how often the speakers used so-called "discourse markers," and concluded that these markers are, indeed, used most frequently by women and girls.
Indeed, the most frequently used organizational strategies are establishing new forms of collaboration with research centers or clients, using new methods of integration with suppliers and outsourcing an organization's own services (OCDE 2005).
Indeed, the most frequently observed mutation in our study was L83V which is detected in 65% of cases (67/103), either alone (15.5% of cases) or along with other mutations (49.5% of cases).
Indeed, the most frequently cited allelochemicals from cyanobacteria are the hapalindoles and related alkaloids: 12-epi-hapalindole and isonitrile, including ambiguines, welwitindolinones and fischerindoles that have been isolated from both marine and freshwater representatives of the family Stigonemataceae, and particularly the genera Hapalosiphon sp. and Fischerella sp. [ 53].
Because NF2 and CDKN2A are indeed the genes most frequently mutated in MPM, blocking PI3K/mTOR signaling might be a valid approach to circumvent the difficulty of applying targeted therapy in the absence of an identified oncogene.
Indeed, opioids are the most frequently used analgesics in ICUs, and IV opioids, such as fentanyl, hydromorphone, and remifentanil, can be considered the first-line drug class of choice to treat nonneuropathic pain in critically ill patients [69].
Indeed, none of the most frequently quoted references of group C1 was quoted by group C2.
Indeed, 'pain' was the most frequently used key word throughout the interviews.
Indeed, the neoplastic diseases most frequently observed in the general population have an almost identical incidence in transplant recipients.
Indeed, opioids are the most frequently used analgesics in ICUs, and IV opioids, such as fentanyl, hydromorphone, and remifentanil, can be considered the first-line drug class of choice to treat nonneuropathic pain in critically ill patients [ 69].
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