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Indeed, differentiation therapy is considered a promising approach for curing human cancers42.
Indeed, differentiation of iPSC into airway epithelium and alveoli is based on the use of biomimetics of normal embryonic and fetal lung development.
Indeed, differentiation was enhanced when OPCs were cultured for 3 days in media supplemented with 90 ng ml−1 FGF1, 35 ng ml−1 FGF2 and cholesterol (exemplifying cuprizone+cholesterol chow), in comparison to 45 ng ml−1 FGF1 and 80 ng ml−1 FGF2 (exemplifying cuprizone+normal chow) (Fig. 7i).
Indeed, differentiation of SH-SY5Y cells by retinoic acid leads to the induction of PTB1 [9], but not the neural isoform, nPTB (data not shown).
Indeed, differentiation therapy with the retinoid all-trans retinoic acid is successfully used as standard treatment of acute promyelocytic leukemia patients 50.
Indeed, differentiation therapy has been very successful in curing acute promyeloid leukemia (APL), which characteristically bears t(15 17) translocation and produces promyelocytic leukemia retinoic acid receptor α fusion protein.
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Indeed, this differentiation is crucial since it greatly affects the results, which is illustrated in Figure 3a.
Indeed, that differentiation could help E27 increase its circulation numbers, which sources close to the company told TechCrunch are significantly below the 2.4 million monthly pageviews that Tech In Asia recently claimed it receives across its websites.
Indeed, the differentiation of iPSCs into SMCs has been recently reported [55].
Indeed, neuronal differentiation from mouse and human stem cells was induced by cell-cell contact and cells deficient in Cx43 show aberrant specification [30], [31].
Indeed, ongoing differentiation is a routine feature of EpiSC cultures.
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