Sentence examples for indeed deletions from inspiring English sources

Indeed, deletions involving long-range regulatory regions containing Conserved Non-Genic sequences (CNGs) have recently been reported at the constitutional level as a cause of BPES [9], [20].

Indeed, deletions of p47phox and gp91phox subunits of NADPH oxidase inhibited superoxide generation in the aorta of ApoE−/− mice, but the effects on atherosclerosis were equivocal [14] [16]; over-expression of Cu/Zn superoxide dismutase (SOD), which converts superoxide to hydrogen peroxide, did not attenuate atherosclerosis in ApoE−/− mice [17].

Indeed, deletions encompassing both genes (BRCA1 and beclin-1) and deletions of only BRCA1 but not beclin-1 were found in breast and ovarian cancers, which is consistent with BRCA1 loss representing the primary driver mutation in these cancers.

The fact that 88 out of 95 mutants resulted in predicted BglII restriction profiles suggests that indeed deletions of a unique fragment of contiguous WD40 repeat sequences is the most frequent event.

Indeed, deletion of these genes in IMS0002 caused a 21% reduction of the maximum specific growth rate on arabinose.

Indeed, deletion of DDAH-1 gene, or the inhibition of its transcription, is associated with an increase of ADMA levels [48].

Indeed, deletion of UBC13 causes a 25-fold increase in the spontaneous mutation rate; when these ubc13 mutant cells were transformed with a plasmid containing OsUbc13, the spontaneous mutation rate was reduced to about fivefold (Table 1).

Indeed, deletion of these genes in the fission yeast S. pombe disrupts histone methylation and centromere formation, causing slow or stalled anaphase during cell division.

Indeed, deletion of the mpl gene and other genes involved in peptidoglycan recycling increases antibiotic susceptibility of some pathogenic strains.

Indeed, deletion of the respective 11 amino acids in the human V2R (referred to as human del243 253) had no effect on receptor function (Table 2).

Indeed, deletion of the FKH domain leads to an increase in the amount of protein in the cytoplasm and thus appears to facilitate the interaction between the proteins.