Indeed, IFI16 detects abortive reverse transcription products in resting CD4+ T cells, which initiates a pro-inflammatory form of programmed cell death called pyroptosis 73, 74.
There have been abortive attempts so far.
Indeed, this mechanism of controlled cytokinesis failure or abortive cytokinesis has been employed in mammalian developmental programs such as cardiomyocyte binucleation (Engel et al., 2006), hepatocyte tetraploidization (Margall-Ducos et al., 2007), and megakaryocyte polyploidization (Lordier et al., 2008).
So she never received triptan for abortive treatment.
In the presence of SP600125, indeed, WT cells did not manifest a mitotic arrest but typically underwent one round of abortive mitosis featuring a transient phase of chromatin condensation but not a symmetric metaphase plate, followed by karyokinesis failure, no cytokinesis and either quiescence (no further mitosis) or cell death (Fig 5A and B and Video 1 of Supporting Information).
Indeed, in DAPI-stained pollen grains from p5cs1 p5cs2/P5CS2, no nuclei were ever observed in the small and abortive pollen grains, while up to three nuclei can be seen in the large and normal-looking pollen grains, as in normal pollen.
Another explanation is exonization [77], [78]; indeed, the presence of read-through or R-transcripts [79] [81] in AChE could be considered a nascent or abortive exonization event, and the low abundance of such R-transcripts is consistent with an exonization process [78].
Indeed, for far too long the arsenal of treatments for CH has been limited to triptans and oxygen amongst abortive treatments, and verapamil, corticosteroids and lithium for CH prevention.
Efforts by Swedes and Prussians proved abortive.
