This impacts significantly upon many of the metabolites upstream of cholesterol and upon the non-sterol arms, thereby incurring off-target effects.
Jane Austen's comic novels end in marriage; Tyler's bittersweet one begins with the marriage of her two "amateurs," Michael Anton and Pauline Barclay, who are thrown together when Pauline is brought into the Anton grocery store for treatment of a wound she's incurred jumping off a streetcar to join an enlistment parade.
The unexpected costs you might incur on a day off can totally derail your weekday frugality.
"Our performance in the second half of the year to date has been below expectations, as a result of a slowdown in specific trading businesses, one-off costs incurred on the Transport for London congestion charging contract and continued delays in client decision-making".
It incurred one-off redundancy costs of £10m in the second half, following £14m in the first half.
The programme will incur one-off costs of up to £30m, plus capital investments of £10m in relation to new systems and buildings.
In its first full year under Branson's full control VOP incurred one-off costs of nearly £80m, including some £20m set aside to cover unsold stock.
Total closure of both plants would incur one-off costs in excess of £100m (based on what was provided for the closure of McIntosh in 2009).
As defenses are costly and thought to incur trade-offs for plant growth and reproduction [ 1], we evaluated if silencing SIPK and WIPK benefited plant growth and fitness.
Yes, they had mortgages and big legal bills incurred while fending off G.O.P.-inspired investigations, but they also had enormous earning power.
Hospitals providing DGA services are usually in large urban centers, meaning families living in rural/remote locations may face financial pressure incurred by time off from work, childcare, travel and accommodation.
