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Furthermore, by defining an index called the Failure Extent Index (FEI) Fm, the incremental ratio of plastic energy and elastic energy, two mainly failure modes, namely the progressive and catastrophic, are studied.
The mobile screening unit had an incremental ratio of £18 000/QALY gained, whereas the case management component had an incremental ratio of £4100/QALY gained.
Considering the incremental cost effectiveness of intensive compared with conventional glycaemic control, the more intensive strategy had an incremental ratio of around $Int16 900.
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Lastly we plotted the mean incremental ratio (±95% confidence interval) on the log scale for the trial data compared to the incremental ratios of the genuine and modified Fibonacci series.
In the most unfavourable (and highly unlikely) scenario, which combined all the unfavourable assumptions, the mobile screening unit and case management components had incremental ratios of £26 000/QALY gained and £6800/QALY gained, respectively.
Furthermore, it presents the incremental cost, the incremental effectiveness, and the incremental cost-effectiveness ratio of each algorithm compared to the next least-effective.
In the incremental analysis, increased taxation had an incremental cost effectiveness ratio of around $Int140 per DALY averted compared with the status quo; adding a ban on advertising produced an incremental cost effectiveness ratio of $Int2800.
If the proportion of patients attending the HIV clinic for the first time with CD4+ count ≤50 cells/µl increased by 25% to 97.3% of the clinic population (vs. 81% in the basecase analysis), the incremental cost-effectiveness ratio of both interventional strategies decreased and especially the incremental cost-effectiveness ratio of prophylaxis vs. screening decreased to 478 $/LYG.
This resulted in incremental costs for ticagrelor of EUR 560 and an incremental cost-effectiveness ratio of EUR 3,118 per year of life gained.
A strategy 'A' was considered weakly dominated by another strategy 'B' when the incremental cost-effectiveness ratio of the strategy 'A' vs. the comparator (i.e. no intervention) was higher than the incremental cost effectiveness ratio of the strategy 'B' vs. the strategy 'A'.
The incremental cost-effectiveness ratio of implementation of the ultra short stay programme versus 'doing nothing' will be expressed as the incremental cost per QALY.
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