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NNs based on the radial basis function and multilayer perceptron, used to predict incremental joint angles, were proposed by Chiddarwar et al. and K.K. Dash et al., respectively (Chiddarwar and Ramesh Babu 2010; Dash et al. 2011).
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51 The degree of uncertainty surrounding the ICERs was summarized by scatter plots of joint incremental costs and incremental effects (change in the number of correctly treated fever patients) and cost-effectiveness acceptability curves.
The aim is to maximise the precision of estimates of these parameters (or, alternatively, to minimise bias in their estimation), so that residual uncertainty associated with estimates of incremental cost-effectiveness (joint costs and effects) is minimised.
32 Within each risk-defined subgroup, the analytic comparison focused on the joint estimation of incremental costs and incremental QALYs (with increments calculated as the intervention group value minus the control group value).
The CEAC is derived from the joint distribution of incremental costs and incremental effects.
Figure 3 shows the joint distribution of incremental costs and incremental systolic BP point reduction generated by the bootstrap replicates.
We derived the CEAC from the joint distribution of incremental costs and incremental effects; we used non-parametric bootstrapping of the observed data to estimate these joint distributions.
Figure 2 and online supplementary figure S1 show the cost-effectiveness planes comparing the joint density of incremental costs and incremental effects for 10 000 model iterations.
These were presented graphically on a cost-effectiveness plane to show the estimated joint distribution of incremental costs against incremental effects and evaluated using net benefit analysis [ 15].
The CEAC is derived from the joint distribution of incremental costs and incremental effects, as estimated by non-parametric bootstrapping of the observed data [ 15].
Scatterplots showing the joint distribution of incremental costs and incremental effects between comparison groups for each of the main outcomes will be calculated.
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