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We raised the hypothesis that FMD would be impaired in the diabetic patients, with incremental impairment in those without SMI, those with SMI but no CAD and those with both SMI and CAD.
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The ACTIV in CHF and EVEREST trials further demonstrated tolvaptan's ability to reduce congestion without causing incremental renal impairment.
The consequent accumulation of GAGs in all cell types induces organ impairment, with incremental neurodegeneration affecting 50 70% of patients.
If centralized tracking was extended to include unilateral referrals – some of which may indeed result in the diagnosis of bilateral hearing impairment – the incremental cost-effectiveness ratio would presumably be lower.
We found a close relationship between renal function and PWV, suggesting that renal impairment has an incremental negative effect on arterial stiffness in patients with established CAD.
The overall 180-day mortality rate in the total study population increased significantly in relation to the severity of renal impairment (overall hazard ratio [HR] for each incremental increase in renal impairment, 1.5 [1.9] 1.9]; P = 0.001).
In contrast, when behavior problems fall below the impairment threshold, clinicians may instead focus on incremental interventions that make many small improvements over time.
The estimated effects and costs were combined in an ICER to calculate the incremental cost of detecting one additional case of bilateral hearing impairment.
Our simulations predict just this, with incremental deletions of the gene resulting in a severe and sudden growth impairment.
HFD-fed animals displayed significant impairment in glucose tolerance, as evidenced by a 90%% higher incremental glucose AUC (Fig. 4b).
Cognitive impairment and dementia, whose prevalence double with every five-year incremental age increase, are the leading global chronic disease contributors to older persons' disability and dependence [ 5].
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