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Taking the ratio of marginal effects on incremental effectiveness and incremental cost, WTP for an additional LY saved is estimated at: (0.0001570/0.0014147)*100,000 = AUD11,098.
Specifically, it might be the case that some of the marginal effect of incremental effectiveness on the latent dependent variable has been picked up in the coefficients on the age group and cure/prevention dummies.
IGRA is the most effective strategy with an incremental effectiveness of 0.0015 and an incremental cost-effectiveness ratio (ICER) of £15 757 per healthy life year gained.
Even though the incremental effectiveness was relatively low for each patient, the model evaluated the effect of both types of hypertension treatment in all hypertensive patients in our population.
Table 6 also reports marginal effects for the LYs saved version of the population-average model, with incremental effectiveness expressed in terms of LYs saved to permit willingness to pay to be calculated for LYs as well as lives.
Principal outcome measures were average incremental costs, incremental effectiveness, incremental quality-adjusted life years, and net health benefits.
In either of these studies, the ICER figures are likely to be much higher if the incremental effectiveness in these ratios is replaced with figures computed from observational studies that account for the selection bias.
The definition of a willingness to pay threshold for incremental effectiveness is a matter of debate in countries that lack a defined value, as happens in the United Kingdom [38].
Univariate sensitivity analyses showed that the incremental cost (Figure 1) was most sensitive to the cost of antiretroviral medication and that the incremental effectiveness was most sensitive to probability of favorable immune response.
Incremental effectiveness associated with bCPAP was 6.78 life years (LYs).
The incremental effectiveness was 0.0087 quality-adjusted life years (QALY).
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