One of the three guiding principles in the Guide for the Care and Use of Laboratory Animals is that of Refinement, where experimental procedures are increasingly refined to improve the wellbeing of all animals involved [ 44].
Repeated case studies lead to more refined middle range theories that offer increasingly refined information of context conditions, thereby increasing generalisability of such case studies [ 21, 27, 29] and improving our understanding of causal processes [ 35].
High-speed computers and sophisticated "data mining" software are producing increasingly refined visualizations.
And how to quantify "the right stuff" is becoming increasingly refined.
Since the 1930s, scholars have increasingly refined sources, postulated sources behind sources, and many stages of their formation.
As the complexity of animal nervous systems has increased during evolution, developmental control of neuronal connectivity has become increasingly refined.
Yet the tumultuous musical materials become increasingly refined and specific as Mr. Dalbavie explores them in music of shifting moods, pungent harmonies and milky colorings.
What the master was perhaps less aware of – because, as yet, this phenomenon was inchoate – was that throughout the 20th century the editing techniques employed in Hollywood films were being increasingly refined.
In the end,.5: The Gray Chapter picked deftly up from where the band had left off, exhibiting plenty of the usual chaos and cacophony, but balanced by increasingly refined melodies.
Meanwhile, moisture-wicking fabric is becoming increasingly refined.
Details of the underlying mechanisms for mineral precipitation are becoming increasingly refined from studies using atomic-scale microscopy [24, 25, 35, 45, 46].
