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These results suggest that the combination of DTPw HB and Hib vaccines provides an effective means for increasing vaccine coverage in childhood vaccination programmes.
In other words, the vaccination cost is that which is incurred in increasing vaccine coverage by 13.1% to reach 100% coverage.
Increasing vaccine coverage for 12 to 17 year old girls in Germany as described in sensitivity analyses only increased the ICER to 5,807€/QALY.
Increasing vaccine coverage in the recommended population would lead to larger and earlier reductions with only a small impact on the ICER (5,807€/QALY).
The herd effect per avoided case increased with increasing vaccine coverage.
Annual hepatitis A incidence dropped rapidly with increasing vaccine coverage (Fig. 2).
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It is likely that catch-up vaccination campaigns would have helped increase vaccine coverage, and although these are considered inappropriate in France at this time, such campaigns should be considered a primary tool in countries facing similar measles epidemic profiles.
Several studies aiming to identify barriers to MMR vaccination were conducted, and specific interventions to increase vaccine coverage were undertaken, particularly in low-performing districts.
Mass vaccination campaigns and Expanded Program of Immunization (EPI) have increased vaccine coverage in the world with a substantial impact on the reduction of rubella infections, such as CRS.
In this study we investigate the efficacy of intradermal inoculation of yellow fever vaccine at one fifth the amount given subcutaneously, as a potential strategy to reduce costs and increase vaccine coverage in areas with limited amounts of vaccine available for mass vaccination as well as for travellers to these areas.
Taking into account the relevance of safety/tolerability in the compliance with vaccination among the population, and, in the case of Italy, having to increase vaccine coverage up to 95%, as prescribed by PNPV 2012 2014, it has been considered appropriate to assess whether today enough scientific evidences are available to support the use of dTap-IPV booster in preschool age.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com