Sentence examples for increasing unfolding from inspiring English sources

Further elucidating whether the detergents in this process enhance fibril formation by increasing unfolding or providing stability of the incorrectly refolded proteins, or both, will be interesting.

The chemical stability of CobR was assessed by following the unfolding of the protein using intrinsic fluorescence; as denaturant concentration was increased unfolding causes the buried tryptophan inside CobR to become exposed.

43 Regarding the R1 and R2 domains, we found that they have a weak dependence on loading rate changing loading rate from 0.4 to 4 pN/s only increased unfolding force by ~10% (unpublished data).

It is generally accepted that increasing protein unfolding and decreasing intramolecular hydrophobic interactions are crucial to the formation of protein nanoparticles [ 46].

In all, as illustrated in Figure 6d, when cells are exposed to SBF-1, SERCA activity is suppressed, inducing depletion of ER Ca2+ and increase of cytosolic Ca2+, which disturbs ER folding capacity and increases unfolded and misfolded proteins, activating the signaling pathways of UPR response and causing ER stress-associated cell death.

We used its metal chelation capability to selectively increase the unfolding energy barrier for the rate-limiting step during the mechanical unfolding of TNfn3.

The APSP value tends to increase during unfolding or conversely, the APSP tends towards a minimum value during folding.

We then show that this early matrix stiffening correlates with increased molecular unfolding in Fn fibers, as determined by Förster Resonance Energy Transfer.

While globally the average radius increases, local unfolding induces increases in curvature in adjacent sections of the loop.

Stability in the adsorbed phase increased dramatically with increasing loading, and unfolding was nearly undetectable close to the resin saturation capacity.

Driven by economic liberalization and changing technologies, the phenomenon of 'access' is likely to dominate to an increasing extent the unfolding experience of human disease and wellbeing.